Stents
are commonly used in the treatment of blocked arteries. They are tiny
and expandable mesh tubes that hold arteries open and help treat
coronary and peripheral artery diseases. Bioabsorbable stents are
defined as fully biodegradable stents that completely disappear
overtime.
Bioabsorbable stents
can be broadly classified into two main types: polymeric bioabsorbable
stents and metallic alloy bioabsorbable stents. Polymeric bioabsorbable
stents are widely used in cardiovascular devices. Polymers used in
bioabsorbable stents are Poly-L-Lactic acid (PLLA), Poly (D,
L-lactide/glycolide) copolymer (PDLA), Polyglycolic Acid (PGA), and
polycaprolactone. Usage of bioabsorbable polymer coating reduces the
need for extended dual anti-platelet therapy and reduces thrombotic
events. Poly-L-Lactic acid is widely used in medicine and breaks down
lactic acid into natural metabolites in the human body. After that,
Poly-L-Lactic acid enters into Krebs cycle and metabolized carbon
dioxide and water.
Iron
and magnesium are the most frequently used metal alloys used to make
metallic bioabsorbable stents. Factors that determine the
biocompatibility of these metal alloys are their solubility and
degradation products. Magnesium bioabsorbable stents are the most
commonly used metallic alloy stents in disease management as magnesium
is an essential element of the human body. It induces rapid
endothelialization and lowers thrombogenicity. Magnesium bioabsorbable
stents have a lower degradation time of about 2 – 3 months compared to
iron-based bioabsorbale stents.
Geographically,
North America dominates the global bioabsorbable stents market owing to
the increased awareness about the important role played by
bioabsorbable stents in the treatment of coronary ailments in the
region. In addition, technological advancements in bioabsorbable stents
products is also supporting in the growth of this market in North
America. The U.S. represents the largest market for bioabsorbable
stents, followed by Canada, in North America. In Europe, Germany, Italy,
the U.K., and France holds major shares of the bioabsorbable stents
market. However, Asia is expected to exhibit a high growth rate in the
next five years in the global bioabsorbable stents market given the
increasing public awareness about various coronary and peripheral artery
diseases in the region. Japan, China, and India are expected to be the
fastest growing bioabsorbable stents markets in Asia.
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In
recent times, increasing prevalence of coronary and peripheral artery
diseases is the key driver of the global bioabsorbable stents market.
Bioabsorbable stents avoid stent-in-stent procedures. They also
eliminate the need for dual anti-platelet therapies and treat coronary
artery diseases more effectively. Accurate stent placement and low cost
treatment also attract patients to adopt bioabsorbable stents for
disease management.
However,
slow adoption rate of stents in disease management is the key restraint
faced by the global bioabsorbable stents market. High risks of
complications associated with bioabsorbable stents and high selling
price also hampers the market growth. In addition, inadequate
reimbursement policies and presence of substitutes are some of the major
challenges faced by the global bioabsorbable stents market. Rising
number of product launches and increasing mergers and acquisitions
between key players are key trends of this market.
Major
companies operating in the global bioabsorbable stents market are
Abbott Laboratories, Arterial Remodeling Technologies SA, Amaranth
Medical, Inc., BIOTRONIK SE & Co. KG, REVA Medical, Inc., Kyoto
Medical Planning, Co., Ltd., and Elixir Medical Corporation.
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